Zhenghui He

Fenofibrate alleviates the brain edema after traumatic brain injury by enhancing endothelial OXPHOS.

内皮能量代谢与脑外伤后脑水肿

Feng Q, Gao Y, Gu X, Zhao X, Liu X, Ma Z, Qi W, He Z, Han Y, Zhang J, Wang W, Li Z, Zhang D, Huang J, Lin Y, Hui J, Onondari B, Erdenetsetseg G, Mao Q, Jiang J, Zhou Y, Weng W, Zhang Y, Feng J.

Redox Biology 94 104240

Preclinical or experimental study

Junfeng Feng: Co-corresponding author

DOI: 10.1016/j.redox.2026.104240

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin · Jialin Huang · Yingwei Gao · Weiji Weng · Zhenghui He · Yuhan Han · Xiaokun Gu

Intracranial Photostimulation Relieves the Learning and Memory Impairment after Traumatic Brain Injury.

Qi W, Hui J, He Z, Feng Q, Gu X, Wang J, Huang J, Lin Y, Ge B, Weng W, Gao Y, Feng J.

Journal of Neurotrauma 43 (15-16) 1352-1365

Preclinical or experimental study

Junfeng Feng: Co-corresponding author

DOI: 10.1177/08977151251406247

Team members: Junfeng Feng · Yong Lin · Jialin Huang · Yingwei Gao · Weiji Weng · Zhenghui He · Xiaokun Gu

Safety and efficacy of decompressive craniectomy versus standard craniotomy for large acute epidural haematoma with tentorial herniation in China (PREDICT-AEDH): a nationwide, multicentre, open-label, parallel-group, randomised controlled trial.

PREDICT-AEDH：急性硬膜外血肿的手术选择

Feng J, Yang C, Xie L, Jin D, Jiang Q, Wang Y, Zhong C, Huang X, Wang Q, Mao J, Song Y, Bao Y, Huang J, Long L, Luo D, Zhen Y, Zhang L, Yun Q, Liang R, Jia J, Zhao W, Fan X, Pan J, Bie L, Liu J, Zhang Y, Hao H, Tang W, Zhang J, Wang Z, Fang W, Yang L, He Z, Liu M, Jiang J, PREDICT-AEDH investigators.

The Lancet Neurology 25 (7) 645-653

Multicentre randomized controlled trial

Junfeng Feng: First author & co-corresponding author

DOI: 10.1016/s1474-4422(26)00143-2

Team members: Jiyao Jiang · Junfeng Feng · Zhenghui He

Traumatic brain injury in China: an update on epidemiology, care pathways, and clinical research.

中国颅脑创伤：流行病学、诊疗路径与研究进展

Feng JF, Huang XJ, Yang XF, Gao GY, Wang QH, He ZH, Jiang G, Liu JF, Qiu BH, Chen WJ, Zhang YM, Long LS, Wang YH, Zuo Q, Yang LK, Weng WJ, Liu JM, Zhong CL, Jiang JY.

The Lancet Neurology 25 (4) 396-405

Review

Junfeng Feng: First author

DOI: 10.1016/s1474-4422(25)00492-2

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng · Zhenghui He

Dynein-regulated brain transduction of AAV.CAP-B10 via cerebral lateral ventricle enhances hippocampal function after traumatic brain injury through Ngf gene delivery in mice.

Wang JC, Ding SH, He ZH, Huang JL, Weng WJ, Gao YW, Jiang JY, Lin Y, Feng JF.

Experimental Neurology 391 115285

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.expneurol.2025.115285

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin · Jialin Huang · Yingwei Gao · Weiji Weng · Zhenghui He

Integrating the characterisation of traumatic brain injury.

Feng J, He Z, Jiang J.

The Lancet Neurology 24 (6) 475-476

Commentary

Junfeng Feng: First author

DOI: 10.1016/s1474-4422(25)00155-3

Team members: Jiyao Jiang · Junfeng Feng · Zhenghui He

Intraoperative application of an antioxidant nanoparticle-hydrogel targeting microglia regulates neuroinflammation in traumatic brain injury.

靶向脑损伤局部小胶质细胞的抗炎干预

Han Y, Gu J, Xu M, Ma Y, Weng W, Feng Q, He Z, Qi W, Mao Q, Jiang J, Feng J.

Journal of Nanobiotechnology 23 (1) 599

Preclinical or experimental study

Junfeng Feng: Sole corresponding author

DOI: 10.1186/s12951-025-03682-7

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng · Zhenghui He · Yuhan Han

Neurophilic Biomimetic Lipoprotein-Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy.

神经生长因子的脑损伤靶向递送

Huang J, Wang W, Peng Y, Weng W, Wei H, Feng Q, Wang A, Hu M, Li Z, Sun S, He Z, Zhang D, Qi W, Han Y, Ma Z, Hui J, Gong R, Gao Y, Lin Y, Jiang J, Gao X, Feng J.

Advanced Science 12 (42) e09405

Preclinical or experimental study

Junfeng Feng: Sole corresponding author

DOI: 10.1002/advs.202509405

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin · Jialin Huang · Yingwei Gao · Weiji Weng · Zhenghui He · Yuhan Han

Tufm lactylation regulates neuronal apoptosis by modulating mitophagy in traumatic brain injury.

Tufm 乳酰化、线粒体自噬与神经元损伤

Weng W, He Z, Ma Z, Huang J, Han Y, Feng Q, Qi W, Peng Y, Wang J, Gu J, Wang W, Lin Y, Jiang G, Jiang J, Feng J.

Cell Death & Differentiation 32 (3) 530-545

Preclinical or experimental study

Junfeng Feng: Sole corresponding author

DOI: 10.1038/s41418-024-01408-0

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin · Jialin Huang · Weiji Weng · Zhenghui He · Yuhan Han

Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway.

Ma Y, He Z, Wang J, Zheng P, Ma Z, Liang Q, Zhang Q, Zhao X, Huang J, Weng W, Jiang J, Feng J.

iScience 27 (4) 109435

Preclinical or experimental study

Junfeng Feng: Co-corresponding author

DOI: 10.1016/j.isci.2024.109435

Team members: Jiyao Jiang · Junfeng Feng · Jialin Huang · Weiji Weng · Zhenghui He

Temperature induces brain-intake shift of recombinant high-density lipoprotein after traumatic brain injury.

Huang J, Peng Y, Wang X, Gu X, Yi Y, Wang W, He Z, Ma Z, Feng Q, Qi W, Hui J, Gong R, Weng W, Jiang G, Gao Y, Lin Y, Li J, Jiang J, Feng J.

Journal of Nanobiotechnology 22 (1) 769

Preclinical or experimental study

Junfeng Feng: Co-corresponding author

DOI: 10.1186/s12951-024-03016-z

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin · Jialin Huang · Yingwei Gao · Weiji Weng · Zhenghui He · Xiaokun Gu

Traumatic brain injury in elderly population: A global systematic review and meta-analysis of in-hospital mortality and risk factors among 2.22 million individuals.

老年颅脑创伤结局与危险因素的全球证据

Ma Z, He Z, Li Z, Gong R, Hui J, Weng W, Wu X, Yang C, Jiang J, Xie L, Feng J.

Ageing Research Reviews 99 102376

Systematic review and meta-analysis

Junfeng Feng: Co-corresponding author

DOI: 10.1016/j.arr.2024.102376

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng · Zhenghui He

Using Natural Language Processing (GPT-4) for Computed Tomography Image Analysis of Cerebral Hemorrhages in Radiology: Retrospective Analysis.

Zhang D, Ma Z, Gong R, Lian L, Li Y, He Z, Han Y, Hui J, Huang J, Jiang J, Weng W, Feng J.

Journal of Medical Internet Research 26 e58741

Clinical observational or methods study

Junfeng Feng: Sole corresponding author

DOI: 10.2196/58741

Team members: Jiyao Jiang · Junfeng Feng · Jialin Huang · Weiji Weng · Zhenghui He · Yuhan Han

A Perioperative Paradigm of Cranioplasty With Polyetheretherketone: Comprehensive Management for Preventing Postoperative Complications.

He Z, Ma Y, Yang C, Hui J, Mao Q, Gao G, Jiang J, Feng J.

Frontiers in Surgery 9 856743

Clinical observational or methods study

Junfeng Feng: Sole corresponding author

DOI: 10.3389/fsurg.2022.856743

Team members: Jiyao Jiang · Junfeng Feng · Zhenghui He

Brain Extract of Subacute Traumatic Brain Injury Promotes the Neuronal Differentiation of Human Neural Stem Cells via Autophagy.

He Z, Lang L, Hui J, Ma Y, Yang C, Weng W, Huang J, Zhao X, Zhang X, Liang Q, Jiang J, Feng J.

Journal of Clinical Medicine 11 (10) 2709

Preclinical or experimental study

Junfeng Feng: Sole corresponding author

DOI: 10.3390/jcm11102709

Team members: Jiyao Jiang · Junfeng Feng · Jialin Huang · Weiji Weng · Zhenghui He

Direct Current Electric Field Coordinates the Migration of BV2 Microglia via ERK/GSK3β/Cofilin Signaling Pathway.

Ma Y, Yang C, Liang Q, He Z, Weng W, Lei J, Skudder-Hill L, Jiang J, Feng J.

Molecular Neurobiology 59 (6) 3665-3677

Preclinical or experimental study

Junfeng Feng: Sole corresponding author

DOI: 10.1007/s12035-022-02815-5

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng · Zhenghui He

Epidemiological Characteristics of Older Patients with Traumatic Brain Injury in China.

Yang C, Lang L, He Z, Hui J, Jiang J, Gao G, Feng J.

Journal of Neurotrauma 39 (11-12) 850-859

Multicentre observational study

Junfeng Feng: Co-corresponding author

DOI: 10.1089/neu.2021.0275

Team members: Jiyao Jiang · Junfeng Feng · Zhenghui He

Intra-Abdominal Pressure Measurements in Neurocritical Patients.

Xu X, He Z, Shan Y, Mao Q, Feng J, Gao G.

Journal of Visualized Experiments (171)

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.3791/62557

Team members: Junfeng Feng · Zhenghui He