Research archive

Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations.

Huie JR, Mondello S, Lindsell CJ, Antiga L, Yuh EL, Zanier ER, Masson S, Rosario BL, Ferguson AR, Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Participants and Investigators.

Journal of Neurotrauma 38 (18) 2514-2529

Review

Junfeng Feng: Named consortium investigator

DOI: 10.1089/neu.2019.6762

Evaluation of Intracranial Hypertension in Traumatic Brain Injury Patient: A Noninvasive Approach Based on Cranial Computed Tomography Features.

Shan Y, Li Y, Xu X, Feng J, Wu X, Gao G.

Journal of Clinical Medicine 10 (11) 2524

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.3390/jcm10112524

Team members: Junfeng Feng

Influence of aging and increased blood pressure on oscillometric cuff pressure waveform characteristics.

Pan F, He P, Pu X, Gao H, Chen F, Feng J, Zheng D.

Journal of Hypertension 39 (11) 2157-2163

Clinical physiological methods study

Junfeng Feng: Sole corresponding author

DOI: 10.1097/hjh.0000000000002921

Team members: Junfeng Feng

Intra-Abdominal Pressure Measurements in Neurocritical Patients.

Xu X, He Z, Shan Y, Mao Q, Feng J, Gao G.

Journal of Visualized Experiments (171)

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.3791/62557

Team members: Junfeng Feng · Zhenghui He

Prospective Randomized Evaluation of Decompressive Ipsilateral Craniectomy for Traumatic Acute Epidural Hematoma (PREDICT-AEDH): study protocol for a randomized controlled trial.

Yang C, Huang X, Feng J, Xie L, Hui J, Li W, Jiang J.

Trials 22 (1) 421

Study protocol

Junfeng Feng: Author

DOI: 10.1186/s13063-021-05359-6

Team members: Jiyao Jiang · Junfeng Feng

Comparison of Care System and Treatment Approaches for Patients with Traumatic Brain Injury in China versus Europe: A CENTER-TBI Survey Study.

Feng J, van Veen E, Yang C, Huijben JA, Lingsma HF, Gao G, Jiang J, Maas AIR, Collaborative European Neuro Trauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants.

Journal of Neurotrauma 37 (16) 1806-1817

Multicentre survey study

Junfeng Feng: Author

DOI: 10.1089/neu.2019.6900

Team members: Jiyao Jiang · Junfeng Feng

Intracranial Pressure during External Ventricular Drainage Weaning Is an Outcome Predictor of Traumatic Brain Injury.

Gu JC, Wu H, Chen XZ, Feng JF, Gao GY, Jiang JY, Mao Q.

BioMed Research International 2020 8379134

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1155/2020/8379134

Team members: Jiyao Jiang · Junfeng Feng

Tailored Lipoprotein-Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor-Stimulated Macropinocytosis.

Jiang G, Chen H, Huang J, Song Q, Chen Y, Gu X, Jiang Z, Huang Y, Lin Y, Feng J, Jiang J, Bao Y, Zheng G, Chen J, Chen H, Gao X.

Advanced Science 7 (5) 1903290

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1002/advs.201903290

Team members: Jiyao Jiang · Junfeng Feng · Jialin Huang

Tailored Reconstituted Lipoprotein for Site-Specific and Mitochondria-Targeted Cyclosporine A Delivery to Treat Traumatic Brain Injury.

Chen L, Song Q, Chen Y, Meng S, Zheng M, Huang J, Zhang Q, Jiang J, Feng J, Chen H, Jiang G, Gao X.

ACS Nano 14 (6) 6636-6648

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1021/acsnano.9b09186

Team members: Jiyao Jiang · Junfeng Feng · Jialin Huang

Central versus Local Radiological Reading of Acute Computed Tomography Characteristics in Multi-Center Traumatic Brain Injury Research.

Vande Vyvere T, Wilms G, Claes L, Martin Leon F, Nieboer D, Verheyden J, van den Hauwe L, Pullens P, Maas AIR, Parizel PM, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants.

Journal of Neurotrauma 36 (7) 1080-1092

Clinical research article

Junfeng Feng: Named consortium investigator

DOI: 10.1089/neu.2018.6061

Effects of Brain Temperature on the Outcome of Patients with Traumatic Brain Injury: A Prospective Observational Study.

Weng WJ, Yang C, Huang XJ, Zhang YM, Liu JF, Yao JM, Zhang ZH, Wu XS, Mei T, Zhang CD, Jia J, Shi XF, Mao Q, Feng JF, Gao GY, Jiang JY.

Journal of Neurotrauma 36 (7) 1168-1174

Clinical observational or methods study

Junfeng Feng: Co-corresponding author

DOI: 10.1089/neu.2018.5881

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng

Inhibition of ferroptosis attenuates tissue damage and improves long-term outcomes after traumatic brain injury in mice.

Xie BS, Wang YQ, Lin Y, Mao Q, Feng JF, Gao GY, Jiang JY.

CNS Neuroscience & Therapeutics 25 (4) 465-475

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1111/cns.13069

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin

Risk factors of hospital mortality in chronic subdural hematoma: A retrospective analysis of 1117 patients, a single institute experience.

Wang S, Ma Y, Zhao X, Yang C, Gu J, Weng W, Hui J, Mao Q, Gao G, Feng J.

Journal of Clinical Neuroscience 67 46-51

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1016/j.jocn.2019.06.026

Team members: Junfeng Feng · Weiji Weng

Steered migration and changed morphology of human astrocytes by an applied electric field.

Yang C, Wang L, Weng W, Wang S, Ma Y, Mao Q, Gao G, Chen R, Feng J.

Experimental Cell Research 374 (2) 282-289

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.yexcr.2018.11.029

Team members: Junfeng Feng · Weiji Weng

The depth of catheter in chronic subdural haematoma: does it matter?

Weng W, Li H, Zhao X, Yang C, Wang S, Hui J, Mao Q, Gao G, Feng J.

Brain Injury 33 (6) 717-722

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1080/02699052.2018.1531312

Team members: Junfeng Feng · Weiji Weng

Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study.

van Essen TA, den Boogert HF, Cnossen MC, de Ruiter GCW, Haitsma I, Polinder S, Steyerberg EW, Menon D, Maas AIR, Lingsma HF, Peul WC, CENTER-TBI Investigators and Participants.

Acta neurochirurgica 161 (3) 435-449

Clinical research article

Junfeng Feng: Named consortium investigator

DOI: 10.1007/s00701-018-3761-z

Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury.

You W, Tang Q, Wu X, Feng J, Mao Q, Gao G, Jiang J.

Neuroscience Bulletin 34 (4) 639-646

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1007/s12264-018-0241-7

Team members: Jiyao Jiang · Junfeng Feng

Bilateral Mydriasis Secondary to Propofol Administration in a Patient With Hypertensive Cerebellar Hemorrhage.

Weng W, Gao W, Zhao X, Mao Q, Gao G, Feng J.

Journal of Neurosurgical Anesthesiology 30 (3) 278-279

Case report

Junfeng Feng: Author

DOI: 10.1097/ana.0000000000000411

Team members: Junfeng Feng · Weiji Weng

Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study.

van Veen E, van der Jagt M, Cnossen MC, Maas AIR, de Beaufort ID, Menon DK, Citerio G, Stocchetti N, Rietdijk WJR, van Dijck JTJM, Kompanje EJO, CENTER-TBI investigators and participants.

Critical Care 22 (1) 306

Clinical research article

Junfeng Feng: Named consortium investigator

DOI: 10.1186/s13054-018-2241-4

Circular RNA Expression Profiles Alter Significantly after Traumatic Brain Injury in Rats.

Xie BS, Wang YQ, Lin Y, Zhao CC, Mao Q, Feng JF, Cao JY, Gao GY, Jiang JY.

Journal of Neurotrauma 35 (14) 1659-1666

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2017.5468

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin

Comprehensive Proteomic Profiling of Patients' Tears Identifies Potential Biomarkers for the Traumatic Vegetative State.

Tang Q, Zhang C, Wu X, Duan W, Weng W, Feng J, Mao Q, Chen S, Jiang J, Gao G.

Neuroscience Bulletin 34 (4) 626-638

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1007/s12264-018-0259-x

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng

Polarization of Microglia to the M2 Phenotype in a Peroxisome Proliferator-Activated Receptor Gamma-Dependent Manner Attenuates Axonal Injury Induced by Traumatic Brain Injury in Mice.

Wen L, You W, Wang H, Meng Y, Feng J, Yang X.

Journal of Neurotrauma 35 (19) 2330-2340

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2017.5540

Team members: Junfeng Feng

Variation in Blood Transfusion and Coagulation Management in Traumatic Brain Injury at the Intensive Care Unit: A Survey in 66 Neurotrauma Centers Participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study.

Huijben JA, van der Jagt M, Cnossen MC, Kruip MJHA, Haitsma IK, Stocchetti N, Maas AIR, Menon DK, Ercole A, Maegele M, Stanworth SJ, Citerio G, Polinder S, Steyerberg EW, Lingsma HF, CENTER-TBI Investigators and Participants.

Journal of Neurotrauma 35 (2) 323-332

Clinical observational or methods study

Junfeng Feng: Named consortium investigator

DOI: 10.1089/neu.2017.5194

Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study.

Huijben JA, Volovici V, Cnossen MC, Haitsma IK, Stocchetti N, Maas AIR, Menon DK, Ercole A, Citerio G, Nelson D, Polinder S, Steyerberg EW, Lingsma HF, van der Jagt M, CENTER-TBI investigators and participants.

Critical Care 22 (1) 90

Clinical observational or methods study

Junfeng Feng: Named consortium investigator

DOI: 10.1186/s13054-018-2000-6

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients.

Wu X, Gao G, Feng J, Mao Q, Jiang J.

Journal of Visualized Experiments (128)

Methods protocol

Junfeng Feng: Author

DOI: 10.3791/56388

Team members: Jiyao Jiang · Junfeng Feng

Alteration in Long Non-Coding RNA Expression after Traumatic Brain Injury in Rats.

Wang CF, Zhao CC, Weng WJ, Lei J, Lin Y, Mao Q, Gao GY, Feng JF, Jiang JY.

Journal of Neurotrauma 34 (13) 2100-2108

Preclinical or experimental study

Junfeng Feng: Co-corresponding author

DOI: 10.1089/neu.2016.4642

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin · Weiji Weng

Differential radiation response between normal astrocytes and glioma cells revealed by comparative transcriptome analysis.

Gong L, Gu J, Ge J, Wu X, Zhang C, Yang C, Weng W, Gao G, Feng J, Mao Q.

OncoTargets and Therapy 10 5755-5764

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.2147/ott.s144002

Team members: Junfeng Feng · Weiji Weng

Electrical Guidance of Human Stem Cells in the Rat Brain.

Feng JF, Liu J, Zhang L, Jiang JY, Russell M, Lyeth BG, Nolta JA, Zhao M.

Stem Cell Reports 9 (1) 177-189

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.stemcr.2017.05.035

Team members: Jiyao Jiang · Junfeng Feng

Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis.

Huang JL, Jiang G, Song QX, Gu X, Hu M, Wang XL, Song HH, Chen LP, Lin YY, Jiang D, Chen J, Feng JF, Qiu YM, Jiang JY, Jiang XG, Chen HZ, Gao XL.

Nature Communications 8 15144

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1038/ncomms15144

Team members: Jiyao Jiang · Junfeng Feng · Jialin Huang

Mild Hypothermia Promotes Pericontusion Neuronal Sprouting via Suppressing Suppressor of Cytokine Signaling 3 Expression after Moderate Traumatic Brain Injury.

Zhao CC, Wang CF, Li WP, Lin Y, Tang QL, Feng JF, Mao Q, Gao GY, Jiang JY.

Journal of Neurotrauma 34 (8) 1636-1644

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2016.4759

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin

Prevalence of persistent vegetative state in patients with severe traumatic brain injury and its trend during the past four decades: A meta-analysis.

Tang Q, Lei J, Gao G, Feng J, Mao Q, Jiang J.

NeuroRehabilitation 40 (1) 23-31

Systematic review and meta-analysis

Junfeng Feng: Author

DOI: 10.3233/nre-161387

Team members: Jiyao Jiang · Junfeng Feng

Right median nerve electrical stimulation for acute traumatic coma (the Asia Coma Electrical Stimulation trial): study protocol for a randomised controlled trial.

Wu X, Zhang C, Feng J, Mao Q, Gao G, Jiang J.

Trials 18 (1) 311

Study protocol

Junfeng Feng: Author

DOI: 10.1186/s13063-017-2045-x

Team members: Jiyao Jiang · Junfeng Feng

The preventive effect of dexmedetomidine on paroxysmal sympathetic hyperactivity in severe traumatic brain injury patients who have undergone surgery: a retrospective study.

Tang Q, Wu X, Weng W, Li H, Feng J, Mao Q, Gao G, Jiang J.

PeerJ 5 e2986

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.7717/peerj.2986

Team members: Jiyao Jiang · Junfeng Feng · Weiji Weng

Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study.

Cnossen MC, Huijben JA, van der Jagt M, Volovici V, van Essen T, Polinder S, Nelson D, Ercole A, Stocchetti N, Citerio G, Peul WC, Maas AIR, Menon D, Steyerberg EW, Lingsma HF, CENTER-TBI investigators.

Critical Care 21 (1) 233

Clinical research article

Junfeng Feng: Named consortium investigator

DOI: 10.1186/s13054-017-1816-9

Alteration of microRNA expression in cerebrospinal fluid of unconscious patients after traumatic brain injury and a bioinformatic analysis of related single nucleotide polymorphisms.

You WD, Tang QL, Wang L, Lei J, Feng JF, Mao Q, Gao GY, Jiang JY.

Chinese Journal of Traumatology 19 (1) 11-15

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1016/j.cjtee.2016.01.004

Team members: Jiyao Jiang · Junfeng Feng

Intraventricular intracranial pressure monitoring improves the outcome of older adults with severe traumatic brain injury: an observational, prospective study.

You W, Feng J, Tang Q, Cao J, Wang L, Lei J, Mao Q, Gao G, Jiang J.

BMC Anesthesiology 16 (1) 35

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1186/s12871-016-0199-9

Team members: Jiyao Jiang · Junfeng Feng

The Role of Posttraumatic Hypothermia in Preventing Dendrite Degeneration and Spine Loss after Severe Traumatic Brain Injury.

Wang CF, Zhao CC, Jiang G, Gu X, Feng JF, Jiang JY.

Scientific Reports 6 37063

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1038/srep37063

Team members: Jiyao Jiang · Junfeng Feng

Attenuation of Cell Death in Injured Cortex After Post-Traumatic Brain Injury Moderate Hypothermia: Possible Involvement of Autophagy Pathway.

Jin Y, Lin Y, Feng JF, Jia F, Gao G, Jiang JY.

World Neurosurgery 84 (2) 420-430

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.wneu.2015.03.039

Team members: Jiyao Jiang · Junfeng Feng

Glial fibrillary acidic protein as a biomarker in severe traumatic brain injury patients: a prospective cohort study.

Lei J, Gao G, Feng J, Jin Y, Wang C, Mao Q, Jiang J.

Critical Care 19 362

Clinical observational or methods study

Junfeng Feng: Author

DOI: 10.1186/s13054-015-1081-8

Team members: Jiyao Jiang · Junfeng Feng

Moderate Hypothermia Significantly Decreases Hippocampal Cell Death Involving Autophagy Pathway after Moderate Traumatic Brain Injury.

Jin Y, Lin Y, Feng JF, Jia F, Gao GY, Jiang JY.

Journal of Neurotrauma 32 (14) 1090-1100

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2014.3649

Team members: Jiyao Jiang · Junfeng Feng

Rationale, methodology, and implementation of a nationwide multicenter randomized controlled trial of long-term mild hypothermia for severe traumatic brain injury (the LTH-1 trial).

Lei J, Gao G, Mao Q, Feng J, Wang L, You W, Jiang J, LTH-1 trial collaborators.

Contemporary Clinical Trials 40 9-14

Randomized trial protocol

Junfeng Feng: Author

DOI: 10.1016/j.cct.2014.11.008

Team members: Jiyao Jiang · Junfeng Feng

Blockage of the upregulation of voltage-gated sodium channel nav1.3 improves outcomes after experimental traumatic brain injury.

Huang XJ, Li WP, Lin Y, Feng JF, Jia F, Mao Q, Jiang JY.

Journal of Neurotrauma 31 (4) 346-357

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2013.2899

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin

Evaluation of metric, topological, and temporal ordering memory tasks after lateral fluid percussion injury.

Gurkoff GG, Gahan JD, Ghiasvand RT, Hunsaker MR, Van K, Feng JF, Shahlaie K, Berman RF, Lyeth BG, Folkerts MM.

Journal of Neurotrauma 30 (4) 292-300

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2012.2463

Team members: Junfeng Feng

Expression of voltage-gated sodium channel Nav1.3 is associated with severity of traumatic brain injury in adult rats.

Huang XJ, Mao Q, Lin Y, Feng JF, Jiang JY.

Journal of Neurotrauma 30 (1) 39-46

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2012.2508

Team members: Jiyao Jiang · Junfeng Feng · Yong Lin

NAAG peptidase inhibitor improves motor function and reduces cognitive dysfunction in a model of TBI with secondary hypoxia.

Gurkoff GG, Feng JF, Van KC, Izadi A, Ghiasvand R, Shahlaie K, Song M, Lowe DA, Zhou J, Lyeth BG.

Brain research 1515 98-107

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.brainres.2013.03.043

Team members: Junfeng Feng

Guided migration of neural stem cells derived from human embryonic stem cells by an electric field.

Feng JF, Liu J, Zhang XZ, Zhang L, Jiang JY, Nolta J, Zhao M.

Stem Cells 30 (2) 349-355

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1002/stem.779

Team members: Jiyao Jiang · Junfeng Feng

NAAG peptidase inhibitor reduces cellular damage in a model of TBI with secondary hypoxia.

Feng JF, Gurkoff GG, Van KC, Song M, Lowe DA, Zhou J, Lyeth BG.

Brain research 1469 144-152

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.brainres.2012.06.021

Team members: Junfeng Feng

Post-traumatic hypoxia exacerbates neuronal cell death in the hippocampus.

Feng JF, Zhao X, Gurkoff GG, Van KC, Shahlaie K, Lyeth BG.

Journal of Neurotrauma 29 (6) 1167-1179

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1089/neu.2011.1867

Team members: Junfeng Feng

Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-02776, in experimental TBI.

Feng JF, Van KC, Gurkoff GG, Kopriva C, Olszewski RT, Song M, Sun S, Xu M, Neale JH, Yuen PW, Lowe DA, Zhou J, Lyeth BG.

Brain research 1395 62-73

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1016/j.brainres.2011.04.022

Team members: Junfeng Feng

Effect of therapeutic mild hypothermia on the genomics of the hippocampus after moderate traumatic brain injury in rats.

Feng JF, Zhang KM, Jiang JY, Gao GY, Fu X, Liang YM.

Neurosurgery 67 (3) 730-742

Preclinical or experimental study

Junfeng Feng: Author

DOI: 10.1227/01.neu.0000378023.81727.6e

Team members: Jiyao Jiang · Junfeng Feng

Multiple primary primitive neuroectodermal tumours within the spinal epidural space with non-concurrent onset.

Feng JF, Liang YM, Bao YH, Pan YH, Jiang JY.

The Journal of international medical research 36 (2) 366-370

Case report

Junfeng Feng: Author

DOI: 10.1177/147323000803600222

Traumatic subdural effusion evolves into chronic subdural hematoma: two stages of the same inflammatory reaction?

Feng JF, Jiang JY, Bao YH, Liang YM, Pan YH.

Medical Hypotheses 70 (6) 1147-1149

Hypothesis article

Junfeng Feng: Author

DOI: 10.1016/j.mehy.2007.11.014

Team members: Jiyao Jiang · Junfeng Feng

Bcl-2 gene therapy for apoptosis following traumatic brain injury.

Yang XF, Zheng XS, Liu WG, Feng JF.

Chinese Journal of Traumatology 9 (5) 276-281

Preclinical or experimental study

Junfeng Feng: Author